HCBP6 deficiency exacerbates glucose and lipid metabolism disorders in non-alcoholic fatty liver mice
نویسندگان
چکیده
منابع مشابه
Current solutions for obesity-related liver disorders: non-alcoholic fatty liver disease and non-alcoholic steatohepatitis.
o besity is a worldwide epidemic with more than 1 billion overweight adults and at least 300 million obese patients [1]. According to recent statistics from the United States, 16.9% of children and adolescents aged 2–19 years were obese in 2009–2010 and 31.8% were either overweight or obese [2]. The rise in childhood obesity has been accompanied by an increase in pediatric liver diseases: 70%–8...
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Due to the epidemic of obesity across the world, nonalcoholic fatty liver disease (NAFLD) has become one of the most prevalent chronic liver disorders in children and adolescents. NAFLD comprises a spectrum of fat-associated liver conditions that can result in end-stage liver disease and the need for liver transplantation. Simple steatosis, or fatty liver, occurs early in NAFLD and may progress...
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BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is an independent predictor of type 2 diabetes mellitus (T2DM). Insulin resistance and beta-cell dysfunction are involved in the pathogenesis of T2DM. Insulin resistance is associated with NAFLD but little is known about beta-cell dysfunction and NAFLD. AIM We tested whether NAFLD severity is associated with insulin sensitivity and beta-cel...
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Background: The world is now in the process of passing on health to non-diseases chronic, like non-alcoholic fatty liver (NAFLD) is a major cause of changes in the lifestyle of people. This study aims to evaluate the effects of lifestyle on fatty liver disease (NAFLD). Methods: For this critical review, we identified articles by searching original studies and review articles published in peer ...
متن کاملClinical Manifestations and Diagnosis of Non-Alcoholic Fatty Liver Disease
Background & Objective: Nonalcoholic fatty liver diseases (NAFLD) is the major cause of hepatocellular carcinoma and increases the risk of mortality. Understanding the trends of its clinical and biochemical changes is essential to identify patients with NAFLD that are at the greatest risk of nonalcoholic steatohepatitis (NASH) and cirrhosis in Iran. M...
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ژورنال
عنوان ژورنال: Biomedicine & Pharmacotherapy
سال: 2020
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2020.110347